1. L. Stadler, K. Speckner, M. Weiss
    Diffusion of Exit Sites on the Endoplasmic Reticulum: A Random Walk on a Shivering Backbone
    Biophys. J., 115 (8), (2018), 1552-1560
    DOI: 10.1016/j.bpj.2018.09.007
  2. M. Weiss
    A tale about square dancers and maze runners (N&V)
    Nat. Mater., 17, (2018), 655-656
    DOI: 10.1038/s41563-018-0126-1
  3. K. Speckner, L. Stadler, M. Weiss
    Anomalous dynamics of the endoplasmic reticulum network
    Phys. Rev. E, 98 (1), (2018), 012406
    DOI: 10.1103/PhysRevE.98.012406
  4. O. Stiehl, A. Veres, M. Weiss
    Monitoring Subcellular Stress Response via a Cell-permeant Rotor Dye
    J Fluoresc., 28 (2), (2018), 605-613
    DOI: 10.1007/s10895-018-2223-6


  1. L. Stadler, M. Weiss
    Non-equilibrium forces drive the anomalous diffusion of telomeres in the nucleus of mammalian cells
    New J. Phys., 19, (2017), 113048
    DOI: 10.1088/1367-2630/aa8fe1
  2. C.M Ferencz., G. Guigas, A. Veres, B. Neumann, O. Stemmann, M. Weiss
    In vitro reconstitution of the endoplasmic reticulum
    Curr. Prot. Cell Biol., 76, (2017), 11.22.1-11.22.16
    DOI: 10.1002/cpcb.30
  3. R. Fickentscher, M. Weiss
    Physical determinants of asymmetric cell divisions in the early development of Caenorhabditis elegans.
    Sci. Rep., 7, (2017), 9369
    DOI: 10.1038/s41598-017-09690-4
  4. S. Böckler, X. Chelius, N. Hock, T. Klecker, M. Wolter, M. Weiss, R.J. Braun, B. Westermann
    Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates
    J. Cell Biol., 216 (8), (2017), 2481
    DOI: 10.1083/jcb.201611197
  5. H. M. Pan, H. Yu, G. Guigas, A. Fery, M. Weiss, V. Patzel, D. Trau
    Engineering and Design of Polymeric Shells: Inwards Interweaving Polymers as Multilayer Nanofilm, Immobilization Matrix, or Chromatography Resins.
    ACS Appl Mater Inter, 9 (6), (2017), 5447-5456
    DOI: 10.1021/acsami.6b13545


  1. O. Stiehl, M. Weiss
    Heterogeneity of crowded cellular fluids on the meso- and nanoscale
    Soft Matter, 12 (47), (2016), 9413-9416
    DOI: 10.1039/c6sm01436d
  2. R. Fickentscher, P. Struntz, M. Weiss
    Setting the Clock for Fail-Safe Early Embryogenesis
    Phys. Rev. Lett., 117, (2016), 188101
    DOI: 10.1103/PhysRevLett.117.188101
  3. G. Guigas, M. Weiss
    Effects of protein crowding on membrane systems
    BBA Biomembranes, 1858 (10), (2016), 2441-2450
    DOI: 10.1016/j.bbamem.2015.12.021
  4. C. Ferencz, G. Guigas, A. Veres, B. Neumann, O. Stemmann, M. Weiss
    Shaping the endoplasmic reticulum in vitro
    BBA Biomembranes, 1858 (9), (2016), 2035-2040
    DOI: 10.1016/j.bbamem.2016.06.004
  5. M. Huranova, G. Muruganandam, M. Weiss, A. Spang
    Dynamic assembly of the exomer secretory vesicle cargo adaptor subunits
    EMBO Rep., 17 (2), (2016), 202-219
    DOI: 10.15252/embr.201540795
  6. P. Struntz, M. Weiss
    Multiplexed measurement of protein diffusion in Caenorhabditis elegans embryos with SPIM-FCS
    J. Phys. D: Appl. Phys., 49 (4), (2016), 044002
    DOI: 10.1088/0022-3727/49/4/044002


  1. F. Verissimo, A. Halavatyi, R. Pepperkok, M. Weiss
    A microtubule-independent role of p150glued in secretory cargo concentration at endoplasmic reticulum exit sites
    J. Cell Sci., 128 (22), (2015), 4160-4170
    DOI: 10.1242/jcs.172395
  2. N. Schweizer, N. Pawar, M. Weiss, H. Maiato
    An organelle-exclusion envelope assists mitosis and underlies distinct molecular crowding in the spindle region
    J. Cell Biol., 210 (5), (2015), 695-704
    DOI: 10.1083/jcb.201506107
  3. A. J. W. Hartel, M. Glogger, G. Guigas, N. G. Jones, S. F. Fenz, M. Weiss, M. Engstler
    The molecular size of the extra-membrane domain influences the diffusion of the GPI-anchored VSG on the trypanosome plasma membrane
    Scientific Reports, 5, (2015), 10394
    DOI: 10.1038/srep10394
  4. J. Hoffmann, R. Fickentscher, M. Weiss
    Influence of organelle geometry on the apparent binding kinetics of peripheral membrane proteins
    Phys. Rev. E, 91, (2015), 022721
    DOI: 10.1103/PhysRevE.91.022721
  5. K.D. Tillmann, V. Reiterer, F. Baschieri, J. Hoffmann, V. Millarte, M.A. Hauser, A. Mazza, N. Atias, D.F. Legler, R. Sharan, M. Weiss, and Hesso Farhan
    Regulation of Sec16 levels and dynamics links proliferation and secretion
    J. Cell Sci., 128, (2015), 670-682
    DOI: 10.1242/jcs.157115
  6. O. Stiehl, K. Weidner-Hertrampf, M. Weiss
    Macromolecular crowding impacts on the diffusion and conformation of DNA hairpins
    Phys. Rev. E, 91, (2015), 012703
    DOI: 10.1103/PhysRevE.91.012703
  7. G. Guigas, M. Weiss
    Membrane protein mobility depends on the length of extra-membrane domains and on protein concentration
    Soft Matter, 11 (1), (2015), 33-37
    DOI: 10.1039/C4SM01846J


  1. M. Safra, R. Fickentscher, M. Levi-Ferber, Y.M. Danino, A. Haviv-Chesner, M. Hansen, T. Juven-Gershon, M. Weiss, S. Henis-Korenblit
    The FOXO Transcription Factor DAF-16 Bypasses ire-1 Requirement to Promote Endoplasmic Reticulum Homeostasis
    Cell Metab., 20 (5), (2014), 870-881
    DOI: 10.1016/j.cmet.2014.09.006
  2. N. Pawar, C. Donth, M. Weiss
    Anisotropic Diffusion of Macromolecules in the Contiguous Nucleocytoplasmic Fluid during Eukaryotic Cell Division
    Curr. Biol., 24 (16), (2014), 1905-1908
    DOI: 10.1016/j.cub.2014.06.072
  3. D. Ernst, J. Köhler, M. Weiss
    Probing the type of anomalous diffusion with single-particle tracking
    Phys. Chem. Chem. Phys., 16 (17), (2014), 7686-7691
    DOI: 10.1039/C4CP00292J
  4. N. Schweizer, M. Weiss, H. Maiato
    The dynamic spindle matrix
    Curr Opin Cell Biol., 28, (2014), 1-7
    DOI: 10.1016/
  5. M. Weiss
    Crowding, Diffusion, and Biochemical Reactions
    Int. Rev. Cell Mol. Biol., 307, (2014), 383-417
    DOI: 10.1016/B978-0-12-800046-5.00011-4


  1. O. Stiehl, K. Weidner-Hertrampf, M. Weiss
    Kinetics of conformational fluctuations in DNA hairpin-loops in crowded fluids
    New J. Phys., 15 (11), (2013), 113010
    DOI: 10.1088/1367-2630/15/11/113010
  2. R. Fickentscher, P. Struntz, M. Weiss
    Mechanical Cues in the Early Embryogenesis of Caenorhabditis elegans
    Biophys. J., 105 (8), (2013), 1735-1736
    DOI: 10.1016/j.bpj.2013.09.005
  3. M. Weiss
    Single-particle tracking data reveal anticorrelated fractional Brownian motion in crowded fluids
    Phys. Rev. E, 88 (1), (2013), 010101(R)
    DOI: 10.1103/PhysRevE.88.010101


  1. D. Morozova, M. Weiss, G. Guigas
    Shape as a determinant of membrane protein cluster formation
    Soft Matter, 8 (47), (2012), 11905-11910
    DOI: 10.1039/c2sm26720a
  2. M. Hanulova, M. Weiss
    Membrane-mediated interactions - a physico-chemical basis for protein sorting
    Mol. Membr. Biol., 29 (5), (2012), 177-185
    DOI: 10.3109/09687688.2012.667838
  3. M. Hanulova, M. Weiss
    Protein sorting and membrane-mediated interactions
    Biophys. Rev., 4 (2), (2012), 117-124
    DOI: 10.1007/s12551-012-0069-8
  4. D. Ernst , M. Hellmann , J. Köhler, M. Weiss
    Fractional Brownian Motion in Crowded Fluids
    Soft Matter, 8 (18), (2012), 4886-4889
    DOI: 10.1039/C2SM25220A
  5. M. Mercker, M. Ptashnyk, J. Kuehnle, D. Hartmanna, M.Weiss, W.Jaeger
    A multiscale approach to curvature modulated sorting in biological membranes
    J. Theor. Biol., 301, (2012), 67-82
    DOI: 10.1016/j.jtbi.2012.01.039
  6. M. Hellmann, D. W. Heermann, M. Weiss
    Enhancing phosphorylation cascades by anomalous diffusion
    EPL, 97 (5), (2012), 58004
    DOI: 10.1209/0295-5075/97/58004


  1. T. Buechling, V. Chaudhary, K. Spirohn, M. Weiss, M. Boutros
    p24 proteins are required for secretion of Wnt ligands
    EMBO Rep., 12, (2011), 1265-1272
    DOI: 10.1038/embor.2011.212
  2. G. Guigas, D. Morozova, M. Weiss
    Exploring Membrane and Protein Dynamics with Dissipative Particle Dynamics
    in: Advances in Protein Chemistry and Structural Biology, 85, (2011), 143-182, ed.: Ch. Christov, Academic Press, Burlington, ISBN:978-0-12-386485-7
    DOI: 10.1016/B978-0-12-386485-7.00004-1
  3. R. Berkovich, H. Wolfenson, S. Eisenberg, M. Ehrlich, M. Weiss, J. Klafter, Y.I. Henis, M. Urbakh
    Accurate Quantification of Diffusion and Binding Kinetics of Non-integral Membrane Proteins by FRAP
    Traffic, 12 (11), (2011), 1648-1657
    DOI: 10.1111/j.1600-0854.2011.01264.x
  4. D. Morozova, G. Guigas, M. Weiss
    Dynamic Structure Formation of Peripheral Membrane Proteins
    PLoS Comput Biol, 7 (6), (2011), e1002067
    DOI: 10.1371/journal.pcbi.1002067
  5. M. Hellmann, J. Klafter, D. W. Heermann, M. Weiss
    Challenges in determining anomalous diffusion in crowded fluids
    J. Phys.: Condens. Matter, 23 (23), (2011), 234113
    DOI: 10.1088/0953-8984/23/23/234113
  6. U. Schmidt, M. Weiss
    Anomalous diffusion of oligomerized transmembrane proteins
    J.Chem. Phys., 134 (16), (2011), 165101-165105
    DOI: 10.1063/1.3582336
  7. M. Hellmann, D. W. Heermann, M. Weiss
    Anomalous reaction kinetics and domain formation on crowded membranes
    EPL, 94 (1), (2011), 18002
    DOI: 10.1209/0295-5075/94/18002


  1. N. Malchus, M. Weiss
    Anomalous diffusion reports on the interaction of misfolded proteins with the quality control machinery in the endoplasmic reticulum
    Biophys. J., 99 (4), (2010), 1321-1328
    DOI: 10.1016/j.bpj.2010.06.020
  2. U. Schmidt, M. Weiss
    Hydrophobic-mismatch induced clustering as a primer for protein sorting in the secretory pathway
    Biophys. Chem., 151 (1), (2010), 34-38
    DOI: 10.1016/j.bpc.2010.04.009
  3. Jens Kühnle, J. Shillcock, O.G. Mouritsen, M. Weiss
    A modeling approach to the self-assembly of the Golgi apparatus
    Biophys. J., 98 (12), (2010), 2839-2847
    DOI: 10.1016/j.bpj.2010.03.035
  4. F. Kapahnke, U. Schmidt, D.W. Heermann, M. Weiss
    Polymer translocation through a nanopore: The effect of solvent conditions
    J. Chem. Phys., 132 (16), (2010), 164904
    DOI: 10.1063/1.3400650
  5. D. Morozova, M. Weiss
    On the role of acylation of transmembrane proteins
    Biophys. J., 98 (5), (2010), 800-804
    DOI: 10.1016/j.bpj.2009.11.014
  6. N. Malchus, M. Weiss
    Elucidating anomalous protein diffusion in living cells with fluorescence correlation spectroscopy - facts and pitfalls
    J. Fluor., 20 (1), (2010), 19-26
    DOI: 10.1007/s10895-009-0517-4
  7. J. Winkler, A. Seybert, L. Koenig, S. Pruggnaller, U. Haselmann, V. Sourjik, M. Weiss, A.S. Frangakis, A. Mogk, B. Bukau
    Quantitative and spatio-temporal features of protein aggregation in E. coli and consequences on protein quality control and cellular aging
    EMBO J., 29, (2010), 910-923
    DOI: 10.1038/emboj.2009.412


  1. J. Szymanski, C. Mayer, U. Hofmann-Rohrer, C. Kalla, I. Grummt, M. Weiss
    Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress
    Biochim. Biophys. Acta, 1793 (7), (2009), 1191-1198
    DOI: 10.1016/j.bbamcr.2009.05.004
  2. J. Szymanski, M. Weiss
    Elucidating the origin of anomalous diffusion in crowded fluids
    Phys. Rev. Lett., 103 (3), (2009), 038102
    DOI: 10.1103/PhysRevLett.103.038102
  3. M. Hellmann, Y. Deng, M. Weiss, D.W. Heermann
    Phase transition of a two-dimensional, multiplicatively coupled XY-Potts model
    J. Phys. A, 42 (22), (2009), 225001
    DOI: 10.1088/1751-8113/42/22/225001


  1. U. Schmidt, G. Guigas, M. Weiss
    Cluster formation of transmembrane proteins due to hydrophobic mismatching
    Phys. Rev. Lett., 101 (12), (2008), 128104
    DOI: 10.1103/PhysRevLett.101.128104
  2. G. Guigas, M. Weiss
    Influence of hydrophobic mismatching on membrane protein diffusion
    Biophys. J., 95 (3), (2008), L25-L27
    DOI: 10.1529/biophysj.108.136069
  3. H. Farhan, M. Weiss, K. Tani, M. Tagaya, R.J. Kaufman, H.-P. Hauri
    Adaptation of endoplasmic reticulum exit sites to acute and chronic increases in cargo load
    EMBO J., 27, (2008), 2043-2054
    DOI: 10.1038/emboj.2008.136
  4. M. Weiss
    Probing the interior of living cells with fluorescence correlation spectroscopy
    Ann. NY Acad. Sci., 1130, (2008), 21-27
    DOI: 10.1196/annals.1430.002
  5. S. Heinzer, S. Woerz, C. Kalla, K. Rohr, M. Weiss
    A model for the self-organization of exit sites in the endoplasmic reticulum
    J. Cell Sci., 121 (1), (2008), 55-64
    DOI: 10.1242/jcs.013383
  6. G. Guigas, M. Weiss
    Sampling the cell with anomalous diffusion - the discovery of slowness
    Biophys. J., 94 (1), (2008), 90-94
    DOI: 10.1529/biophysj.107.117044


  1. G. Guigas, C. Kalla, M. Weiss
    The degree of macromolecular crowding in the cytoplasm and nucleoplasm of mammalian cells is conserved
    FEBS Lett., 581 (26), (2007), 5094-5098
    DOI: 10.1016/j.febslet.2007.09.054
  2. M. Hellmann, M. Weiss, D.W. Heermann
    Monte Carlo simulations reveal the straightening of an end-grafted flexible chain with a rigid side chain
    Phys. Rev. E, 76 (2), (2007), 021802
    DOI: 10.1103/PhysRevE.76.021802
  3. G. Guigas, C. Kalla, M. Weiss
    Probing the Nanoscale Viscoelasticity of Intracellular Fluids in Living Cells
    Biophys. J., 93 (1), (2007), 316-323
    DOI: 10.1529/biophysj.106.099267


  1. G. Guigas, M. Weiss
    Size-Dependent Diffusion of Membrane Inclusions
    Biophys. J., 91 (7), (2006), 2393-2398
    DOI: 10.1529/biophysj.106.087031
  2. M. Prummer, M. Weiss
    Bulk fluorescence measurements cannot probe the survival time distribution of single molecules
    Phys. Rev. E, 74 (2), (2006), 021115
    DOI: 10.1103/PhysRevE.74.021115
  3. O.G. Mouritsen, T.L. Andresen, A. Halperin, P.L. Hansen, A.F. Jakobsen, U.B. Jensen, M. Jensen, K. Jorgensen, T. Kaasgaard, C. Leidy, A.C. Simonsen, G.H. Peters, M. Weiss
    Activation of interfacial enzymes at membrane surfaces
    J. Phys. Condens. Mat., 18 (28), (2006), 1293-1304
    DOI: 10.1088/0953-8984/18/28/S12
  4. H. Runz, K. Miura, M. Weiss, R. Pepperkok
    Sterols regulate ER-export dynamics of secretory cargo protein ts-O45-G
    EMBO J., 25, (2006), 2953-2965
    DOI: 10.1038/sj.emboj.7601205
  5. M. Weiss, A. Mendez-Bermudez, T. Kottos
    Resonance width distribution for high-dimensional random media
    Phys. Rev. B, 73 (4), (2006), 045103
    DOI: 10.1103/PhysRevB.73.045103
  6. R. Forster, M. Weiss, T. Zimmerman, E.G. Reynaud, F. Verissimo, D.J. Stephens, R. Pepperkok
    Secretory Cargo Regulates the Turnover of COPII Subunits at Single ER Exit Sites
    Curr. Biol., 16 (2), (2006), 173-179
    DOI: 10.1016/j.cub.2005.11.076


  1. A.F. Jakobsen, O.G. Mouritsen, M. Weiss
    Close-up view on the modifications of fluid membranes due to phospholipase A2
    J. Phys. Condens. Mat., 47 (17), (2005), 4015-4024
    DOI: 10.1088/0953-8984/17/47/025
  2. A.C. Rowat, L.J. Foster, M.M. Nielsen, M. Weiss, J.H. Ipsen
    Characterization of the elastic properties of the nuclear envelope
    J. R. Soc. Interface, 2, (2005), 63-69
    DOI: 10.1098/rsif.2004.0022


  1. M. Weiss, M. Elsner, F. Kartberg, T. Nilsson
    Anomalous Subdiffusion Is a Measure for Cytoplasmic Crowding in Living Cells
    Biophys. J., 87 (5), (2004), 3518-3524
    DOI: 10.1529/biophysj.104.044263
  2. T. Kottos, M. Weiss
    Current Relaxation in Nonlinear Random Media
    Phys. Rev. Lett., 93 (19), (2004), 190604
    DOI: 10.1103/PhysRevLett.93.190604
  3. M. Weiss
    Challenges and artifacts in quantitative photobleaching experiments
    Traffic, 5 (9), (2004), 662-671
    DOI: 10.1111/j.1600-0854.2004.00215.x
  4. M. Weiss, T. Nilsson
    In a mirror dimly: Tracing the movements of molecules in living cells
    Trends in Cell Biol., 14 (5), (2004), 267-273
    DOI: 10.1016/j.tcb.2004.03.012


  1. M. Weiss
    Stabilizing Turing patterns with sub-diffusion in systems with low particle numbers
    Phys. Rev. E, 68 (3), (2003), 036213
    DOI: 10.1103/PhysRevE.68.036213
  2. M. Elsner, H. Hashimoto, J. Simpson, D.Cassel, T. Nilsson, M. Weiss
    Spatiotemporal dynamics of the COPI vesicle machinery
    EMBO reports, 4 (10), (2003), 1000-1004
    DOI: 10.1038/sj.embor.embor942
  3. M. Weiss, H. Hashimoto, T. Nilsson
    Anomalous Protein Diffusion in Living Cells as Seen by Fluorescence Correlation Spectroscopy
    Biophys. J., 84 (6), (2003), 4043-4052
    DOI: 10.1016/S0006-3495(03)75130-3
  4. M. Weiss, L. Hufnagel, R. Ketzmerick
    Can simple renormalization theories describe the trapping of chaotic trajectories in mixed systems?
    Phys. Rev. E, 67 (4), (2003), 046209
    DOI: 10.1103/PhysRevE.67.046209
  5. M. Weiss, T. Nilsson
    A Kinetic Proof-reading Mechanism for Protein Sorting
    Traffic, 4 (2), (2003), 65-73
    DOI: 10.1034/j.1600-0854.2003.40202.x


  1. M. Weiss, L. Hufnagel, R. Ketzmerick
    Universal Power-Law Decay in Hamiltonian Systems?
    Phys. Rev. Lett., 89 (23), (2002), 239401
    DOI: 10.1103/PhysRevLett.89.239401
  2. T. Kottos, M. Weiss
    Statistics of Resonances and Delay Times: A Criterion for Metal-Insulator Transitions
    Phys. Rev. Lett., 89 (5), (2002), 056401
    DOI: 10.1103/PhysRevLett.89.056401


  1. J. Lanoix, J. Ouwendijk, A. Stark, E. Szafer, D. Cassel, K. Dejgaard, M. Weiss, T. Nilsson
    Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1
    J. Cell Biol., 155 (7), (2001), 1199-1212
    DOI: 10.1083/jcb.200108017
  2. A. Ossipov, M. Weiss, Tsampikos Kottos, T. Geisel
    Quantum mechanical relaxation of open quasiperiodic systems
    Phys. Rev. B, 64 (22), (2001), 224210
    DOI: 10.1103/PhysRevB.64.224210
  3. L. Hufnagel, R. Ketzmerick, M. Weiss
    Conductance fluctuations of generic billiards: Fractal or isolated?
    EPL, 54 (6), (2001), 703-708
    DOI: 10.1209/epl/i2001-00309-6
  4. M. Weiss, T. Kottos, T. Geisel
    Taming chaos by impurities in two-dimensional oscillator arrays
    Phys. Rev. E, 63 (5), (2001), 056211
    DOI: 10.1103/PhysRevE.63.056211
  5. M. Weiss, T. Kottos, T. Geisel
    Spreading and localization of wavepackets in disordered wires in a magnetic field
    Phys. Rev. B, 63, (2001), 081306
    DOI: 10.1103/PhysRevB.63.081306
  6. R. Ketzmerick, L. Hufnagel, M. Weiss
    Quantum Signatures of Typical Chaotic Dynamics
    Adv. Sol. St. Phys., 41, (2001), 473-481, Springer, Berlin/Heidelberg, ISBN: 978-3-540-42000-2
    DOI: 10.1007/3-540-44946-9_38


  1. L. Hufnagel, M. Weiss, A. Iomin, R. Ketzmerick, S. Fishman, T. Geisel
    Metal-insulator transitions in cyclotron resonance of periodic nanostructures due to avoided band crossings
    Phys. Rev. B, 62 (23), (2000), 15348-15351
    DOI: 10.1103/PhysRevB.62.15348
  2. M. Weiss, T. Nilsson
    Protein sorting in the Golgi apparatus:
    A consequence of maturation and triggered sorting

    FEBS Lett., 486 (1), (2000), 2-9
    DOI: 10.1016/S0014-5793(00)02155-4
  3. R. Ketzmerick, L. Hufnagel, F. Steinbach, M. Weiss
    New Class of Eigenstates in Generic Hamiltonian Systems
    Phys. Rev. Lett., 85 (6), (2000), 1214-1217
    DOI: 10.1103/PhysRevLett.85.1214
  4. M. Weiss, T. Kottos, T. Geisel
    Scaling properties of one-dimensional Anderson models in an electric field: Exponential versus factorial localization
    Phys. Rev. B, 62 (3), (2000), 1765-1772
    DOI: 10.1103/PhysRevB.62.1765


  1. M. Weiss, W. Welsch, M.v. Schickfus, S. Hunklinger
    Viscoelastic Behavior of Antibody Films on a Shear Horizontal Acoustic Surface Wave Sensor
    Anal. Chem., 70 (14), (1998), 2881-2887
    DOI: 10.1021/ac971006i